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Malaria

The disease malaria represents a severe health risk transmitted through mosquitoes that carry Plasmodium parasites. The disease presents a critical public health challenge worldwide while affecting populations most severely in tropical and subtropical areas of Africa, Asia, and Latin America. The disease spreads to humans when infected Anopheles mosquitoes deliver bites which contain one of five Plasmodium species responsible for infection. Human malaria infections are caused by five Plasmodium species namely P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi.

P. falciparum stands as the deadliest malaria species causing most global fatalities from malaria whereas P. vivax generates recurring infections. The signs of malaria appear as fever and chills which are accompanied by headaches, vomiting and muscle pain. When malaria remains untreated it advances to serious health threats including cerebral malaria, anemia and organ failure.

Malaria remains both preventable and treatable yet results in more than 600,000 deaths each year with young children making up the majority of victims. Health authorities deploy insecticide-treated nets alongside indoor residual spraying and antimalarial drugs together with rapid diagnostic testing as malaria control strategies. Continuous research efforts support the creation of vaccines while the RTS,S/AS01 malaria vaccine becomes available across multiple malaria-endemic regions.

The World Health Organization and UNICEF along with national malaria control programs jointly strive to eliminate malaria. The reduction of global malaria burden depends on heightened awareness of prevention methods along with timely diagnosis and effective treatment supported by sustainable prevention strategies.

Life Cycle of Plasmodium species

1. Sexual Cycle 

2. Asexual Cycle

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